Clinical protocols. Personal standards.

A private GLP-1 protocol for those who expect more from their bodies.

Physician-designed. Compounded with precision. Delivered discreetly. Support that fits your life — not the other way around.

Become a member See the protocol
Caliber — compounded GLP-1 vial, applicator pen, and packaging

Physician-led protocol

Free cold-chain delivery

503B compounded medication

No hidden fees, ever

The Caliber pack — open forest-green box with vial, injector pen, member dashboard on tablet, and a clinician on a video call
What arrives

More than a box.
A protocol you can hold.

Cold-chain medication, the app that keeps you on track, and a clinician a tap away. One unboxing, the whole protocol in motion.

  • Compounded semaglutide vial2 mg / 2 mL
  • Pre-measured injector pen27g · single use
  • Member dashboardDose, progress, next shipment
  • Care team on videoSame clinician, every month
  • Companion kitMonth 1 only
For context

Same molecule.
Very different protocol.

Caliber GLP-1 protocol box, vial, and injector
  • Same US-licensed physician each month — not a queue
  • Compounded semaglutide, 503B-grade, cold-chain
  • Dose titrated monthly, side effects managed proactively
  • Quarterly bloodwork at home — included
  • Cancel after any month · no 30-day notice
  • HSA / FSA accepted · no insurance run-around
Generic GLP-1 vial and syringe

Others

  • Rotating clinician queue — different name every month
  • Same dose for everyone — limited titration
  • Side effects handled reactively, often by chatbot
  • Bloodwork sold separately or skipped entirely
  • 30-day notice clauses, retention calls on cancel
  • Pricing climbs once you're locked in
Your physician

The same name.
Every month.

“Most of my patients don't need more discipline. They need a protocol calibrated to their body.”

Julian Vance, MD

Internal medicine · 14 yrs · Board-certified, US-licensed

How it works

Three steps.
No middle-man.

Caliber assessment on a phone
01

Assessment

Five minutes online. No charge.

Physician review on a video call
02

Physician review

A US-licensed physician approves your protocol — typically within 17 hours.

Monthly protocol progress with vial and phone dashboard
03

Monthly optimization

Same clinician, same number. Dose adjusts. Bloodwork moves. You don't.

Safety & provenance

What's in the vial,
and who put it there.

503B Pharmacy

FDA-registered outsourcing facility.

Compounded by Empower Pharmacy under cGMP standards. Batch-tested for potency, sterility, pH, endotoxicity.

Physicians

US-licensed. Named. Yours.

Board-certified, licensed in your state. The same clinician each month — not a rotating queue.

Privacy

HIPAA. LegitScript. Quietly.

No data sold. No targeted advertising on your health data. Ever.

CALIBER

Join 12,000+ members.

Disciplined results, delivered quietly.

12,000+ members and growing
See what's possible for you →

Takes 90 seconds · Private · Clinician-led

Kala — month one
Kala — month six

Kala felt lighter

More energy, less stress.

Verified Caliber member
Morgan — month one
Morgan — month six

Morgan built better habits

Small changes, big impact.

Verified Caliber member
Chris — month one
Chris — month six

Chris regained consistency

Back on track and feeling strong.

Verified Caliber member
Noelle — month one
Noelle — month six

Noelle found momentum

Keeping it simple and sustainable.

Verified Caliber member

Members were compensated for their testimonials. Outcomes vary based on treatment plans, adherence, and individual factors. Caliber provides clinician-led care and medication when appropriate.

Check your fit

See if Caliber is right for you.

Three inputs. Honest answer. A clinician makes the final call during your assessment.

Your starting point

29.5

Your BMI

ft
in
lbs
Check your eligibility →
A Caliber member, mid-protocol

12,000+ on protocol

“It wasn't a transformation. It was just my body again.”

Members in their own words.

Where you land

Underweight < 18.5
Healthy weight 18.5 – 24.9
Overweight 25 – 29.9
Obesity 30 +

Caliber may be a fit. A clinician will confirm during your assessment.

BMI is one input — not a diagnosis. It doesn't account for muscle mass, body composition, or context. A US-licensed clinician determines eligibility based on your full health history during the assessment. Compounded medication. Not FDA-approved.

By the numbers

Why people choose Caliber.
It works.

Calibrated, clinical, and consistent — the metrics that matter to a physician, not just the scale.

Caliber compounded semaglutide vial, held in hand

Compounded semaglutide · 5 mg / 2 mL

−12%

Median body-weight reduction at month 12

NEJM · STEP 1 + 5 pooled

9/10

Members re-up at month 12

Caliber cohort · May 2026

−0.8HbA1c

Average reduction at week 24

NEJM · STEP 2 · n=1,210

17hrs

Median time from assessment to physician-approved protocol

Caliber internal · 2026 YTD
Questions, answered

The questions we get asked most.

Is this the same as Ozempic?
Same active molecule, compounded by a 503B pharmacy under federal exemption while branded supply remains in shortage. Compounded medications are not FDA-approved, though semaglutide as a molecule is.
Will I lose muscle?
Some lean mass loss is normal in any caloric deficit. The protocol includes resistance-training guidance, protein targets, and quarterly body-composition tracking.
Side effects?
Nausea, constipation, fatigue during dose escalations — most resolve within a week. The Companion Kit ships with month one.
Can I cancel?
Yes. After any month. No phone call, no 30-day window. Unopened shipments are refunded.
Why $299?
Lifeforce charges $349 for metabolic optimization without prescriptions. Hone charges $250 for TRT without GLP-1. Caliber includes the medication, titration, companion kit, and quarterly bloodwork — for less than Lifeforce alone.
What states?
Florida, Texas, and Georgia today. We check eligibility against your state at the start of the assessment — if we're not live where you are yet, you can join the waitlist for your state.
How quickly will I see results?
Appetite signaling typically calibrates in the first 4–6 weeks. Bloodwork (HbA1c, fasting insulin, lipids) usually shifts by month three. Body-composition changes follow the metabolic shift, not the other way around. The protocol is built for 12–24 months of stable use.
Do you accept insurance?
No. Caliber is direct-pay — one of the reasons pricing stays transparent and consistent. HSA and FSA cards are accepted. Most members find Caliber significantly cheaper than branded GLP-1s through insurance once deductibles and prior-auth friction are factored in.
What if I'm already on a GLP-1 from another provider?
Tell us in the assessment. Your reviewing physician will pick up where your previous protocol left off — same dose, similar titration cadence — without restarting you at the bottom. Bring your most recent prescription label if you have it.
Do I have to inject myself?
Yes. Semaglutide is a subcutaneous injection — once weekly, into the abdomen or thigh, with a 27-gauge insulin needle. Most members describe it as roughly the discomfort of a thumbnail press. The Companion Kit and your physician walk you through it.
What if I have a question between physician check-ins?
Direct-message your physician from the member portal. Same-day response on weekdays, next business day on weekends. Not a chatbot — the same person who designed your protocol.
Can I pause my protocol?
Yes — pause for travel, surgery, or just a break, in one tap from the portal. Paused months aren't charged. Resume when you're ready; your physician adjusts your re-entry dose if you've been off the protocol for more than four weeks.
Is Caliber appropriate for me?
A US-licensed physician makes that call after your assessment. Caliber is typically prescribed for adults with a BMI of 27+ (with at least one related condition) or 30+ on its own. Compounded semaglutide isn't appropriate during pregnancy or breastfeeding, with a personal/family history of medullary thyroid cancer or MEN 2, or with a few other specific conditions your clinician will screen for.
Is this safe?
Semaglutide has been studied in trials totaling tens of thousands of patients, with cardiovascular outcomes (SELECT, 2023) showing a 20% reduction in major adverse events. Compounded versions are not FDA-approved — our 503B partner (Empower Pharmacy) compounds under cGMP standards with per-batch potency, sterility, pH, and endotoxicity testing.
What if it doesn't work for me?
Most members re-up at month twelve, but if you and your physician agree the protocol isn't right, exit at any time without a fee. Unopened shipments are refunded within 14 days. We don't run a retention play.

Ready when you are.

Five minutes. Reviewed by a physician. No charge until approved.

Take the assessment →